The Grand Prix d’Isbergues is a French cycling race contested in the Pas-de-Calais region on the third sunday of September.

Created in 1945, the race is categorized 1.1 by the UCI and takes part of the UCI Europe Tour calendar since 2005. The Grand Prix d’Isbergues is also a stage for the Coupe de France de cyclisme since 1992.

Arnaud Démare distinguished himself there two times by winning the 2013 and 2014 editions.